Polynucleotides are an advanced regenerative injectable treatment designed to improve overall skin quality rather than simply adding volume. Ideal for patients seeking natural rejuvenation, this treatment supports healthier, stronger skin with improved tone, texture and hydration.
Polynucleotides are derived from purified DNA fragments that stimulate tissue repair and skin regeneration. Unlike traditional fillers, they do not add volume but instead improve the health and function of the skin itself.
This treatment is suitable for the face, neck, under-eye area and other delicate areas where skin quality has declined over time.
Once injected, polynucleotides stimulate fibroblast activity, encouraging collagen production and improving blood flow within the skin. This process supports long-term skin regeneration, helping the skin become more resilient, hydrated and youthful in appearance.
Unlike treatments that focus on adding volume or altering facial structure, polynucleotides work by improving the health and function of the skin itself. This non-surgical injectable treatment stimulates natural regeneration, making it ideal for patients who want subtle, natural-looking rejuvenation without incisions, scarring or downtime.
Following your polynucleotides treatment, it is important to avoid touching or massaging the treated area for at least 24 hours. You should avoid strenuous exercise, saunas and excessive heat for a short period, and keep the skin clean and well hydrated.
Results typically develop over several weeks and can last up to 6 months. A course of treatments may be recommended for best results.
Discomfort is minimal, and a fine needle is used. A topical numbing agent can be applied if required.
Most patients return to normal activities the same day, with only mild redness or swelling.
This treatment is suitable for patients looking to improve skin quality, hydration and early ageing rather than volume.




Simply call us on 028 2826 0418 or email us at enquiries@drjillian.co.uk and we’ll guide you through the process. Alternatively, you can enquire online by clicking the button below.